Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?
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Clostridium difficile is evolving more robust toxicity, repeatedly attacking its victims, and driving the search for alternative therapies to fight the infection.
By forging new relationships and finding novel uses for existing technologies, this year’s top companies are employing creative ways to advance their science.
Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.
Can tumors—which can originate from, and often resemble, chronically inflamed tissue—be curtailed using familiar anti-inflammatory agents, without their side effects?
The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.
Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.
Setting up your own scientific laboratory is no easy task, but this year’s respondents are using their postdoc experiences to prepare for the challenge.
Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
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