Features Articles - cancer, cell & molecular biology and immunology

Targeting DNA

By Jef Akst | June 1, 2012

After 20 years of high-profile failure, gene therapy is finally well on its way to clinical approval.

12 Comments

Underground Supermodels

By Thomas J. Park and Rochelle Buffenstein | June 1, 2012

What can a twentysomething naked mole-rat tell us about fighting pain, cancer, and aging?

12 Comments

Freezing Time

By Vern L. Schramm | May 1, 2012

Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.

15 Comments

Telomeres in Disease

By Rodrigo Calado and Neal Young | May 1, 2012

Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.

15 Comments

Are Cancer Stem Cells Ready for Prime Time?

By Suling Liu, Hasan Korkaya, and Max S. Wicha | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.

48 Comments

What it Takes to Develop Better Drugs for Kids

By J. Steven Leeder | March 1, 2012

Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials. Before these laws were enacted, the US Food and Drug Administration (F

2 Comments

Child-Proofing Drugs

By Edyta Zielinska | March 1, 2012

When children need medications, getting the dosing and method of administration right is like trying to hit a moving target with an untried weapon.

6 Comments

Vitamin D on Trial

By Amy Maxmen | March 1, 2012

Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.

52 Comments