Features Articles - cancer, clinical trials and immunology

Freezing Time

By Vern L. Schramm | May 1, 2012

Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.

Telomeres in Disease

By Rodrigo Calado and Neal Young | May 1, 2012

Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.

15 Comments

Are Cancer Stem Cells Ready for Prime Time?

By Suling Liu, Hasan Korkaya, and Max S. Wicha | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.

48 Comments

What it Takes to Develop Better Drugs for Kids

By J. Steven Leeder | March 1, 2012

Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials. Before these laws were enacted, the US Food and Drug Administration (F

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Are the Kids Alright?

By Bob Grant | March 1, 2012

Two key pieces of legislation, enacted to spur drugmakers into testing pharmaceutical products in children, are up for reauthorization in the US Congress this October. Have they done their jobs?

6 Comments

Child-Proofing Drugs

By Edyta Zielinska | March 1, 2012

When children need medications, getting the dosing and method of administration right is like trying to hit a moving target with an untried weapon.

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Vitamin D on Trial

By Amy Maxmen | March 1, 2012

Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.

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Resolving Chronic Pain

By Claudia Sommer and Frank Birklein | January 1, 2012

The body’s own mechanism for dispersing the inflammatory reaction might lead to new treatments for chronic pain.

76 Comments

A Small Revolution

By Erica Westly | October 1, 2011

In fewer than 15 years, nanomedicine has gone from fantasy to reality.

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Nanomedicine

October 1, 2011

At the nanoscale old materials acquire new properties that International Institute for Nanotechnology Director Chad Mirkin thinks will change the way medicine is practiced.

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