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tag disease medicine drug development clinical trials

Illustration of light blue neurons with white amyloid plaques accumulating on their axons.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
Dan Robitzski | Sep 28, 2022 | 2 min read
The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Drug Development: Clinical Trials
Sam Jaffe | May 18, 2003 | 3 min read
5-Prime | Drug Development: Clinical Trials Who gets tested in Phase I Trials? As many as 80 healthy or sick human beings. Phase I trials occur after animal tissue and whole-animal studies have determined that the agent appears safe and effective for its intended use. This stage discerns mainly whether the agent is safe for humans and provides data to determine the pharmacological effects. Phase I studies, which last from two to six months, are observed closely so that the entire trial can
A gloved hand holds a tweezer and pulls a section of DNA away from a double helix
First Person Dosed in Novel Gene Editing Clinical Trial
Amanda Heidt | Jul 12, 2022 | 4 min read
The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.
Updated
Merck research facility in San Francisco
Antiviral Pill Lowers Risks of COVID-19 Hospitalization, Death
Chloe Tenn | Oct 1, 2021 | 3 min read
Merck reports that its antiviral molnupiravir was effective against early stages of COVID-19 in high-risk patients in a Phase 3 clinical trial.
Illustration of woman looking at floating cells through a telescope
Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity
Jane Buckner, MD and Carla Greenbaum, MD | Mar 1, 2023 | 4 min read
A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.
A triangular sign affixed to a tree displaying the silhouette of a tick.
Newly Developed mRNA Vaccine Protects Against Lyme Disease
Charlene Lancaster, PhD | Nov 13, 2023 | 5 min read
Leveraging the same mRNA platform used for COVID-19 vaccines, researchers generated a vaccine that prevents mice from acquiring Lyme disease.
European Drug Regulator Releases Clinical Trial Data
Ben Andrew Henry | Oct 21, 2016 | 2 min read
In the initial steps of a campaign to make clinical reports publicly available, the European Medicines Agency has published data on two recently approved drugs.
Precision Medicine-Based Biomarkers for Traumatic Brain Injury
Precision Medicine-Based Biomarkers for Traumatic Brain Injury 
The Scientist | Aug 8, 2023 | 1 min read
In this webinar, Dr. Kevin Wang will discuss a precision medicine approach for treating traumatic brain injury which uses phenotype biomarkers to monitor disease course and develop novel therapies.
EXCLUSIVE
Colorful pills and capsules on a calendar background
Clinical Trial Registry Errors Undermine Transparency
Catherine Offord | Aug 2, 2022 | 10 min read
A lack of comprehension among some researchers about how to use ClinicalTrials.gov may be hindering public access to trial information and holding up drug study results, an investigation by The Scientist finds.

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