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image: Lamarck and the Missing Lnc

Lamarck and the Missing Lnc

By | October 1, 2012

Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.


image: Pleasant to the Touch

Pleasant to the Touch

By | September 1, 2012

Scientists hope an understanding of nerve fibers responsive only to gentle touch will give insight into the role the sense plays in social bonding.


image: Best Places to Work Academia, 2012

Best Places to Work Academia, 2012

By | August 1, 2012

On the 10th anniversary of The Scientist’s survey of life science academics, institutions are contending with tighter budgets and larger administrative staffs, while working to sustain and inspire their researchers.


image: Replacement Parts

Replacement Parts

By | August 1, 2012

To cope with a growing shortage of hearts, livers, and lungs suitable for transplant, some scientists are genetically engineering pigs, while others are growing organs in the lab.


image: Targeting DNA

Targeting DNA

By | June 1, 2012

After 20 years of high-profile failure, gene therapy is finally well on its way to clinical approval.


image: Underground Supermodels

Underground Supermodels

By | June 1, 2012

What can a twentysomething naked mole-rat tell us about fighting pain, cancer, and aging?


image: Data Diving

Data Diving

By | May 1, 2012

What lies untapped beneath the surface of published clinical trial analyses could rock the world of independent review.


image: Freezing Time

Freezing Time

By | May 1, 2012

Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.


image: Telomeres in Disease

Telomeres in Disease

By | May 1, 2012

Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.


image: Are Cancer Stem Cells Ready for Prime Time?

Are Cancer Stem Cells Ready for Prime Time?

By | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.


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    Mammals diversified 30 million years later than previously estimated, according to a new analysis of an ancient fossil.

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    The immune system tolerates the colonization of commensal bacteria on the skin with the aid of regulatory T cells during the first few weeks of life, a mouse study shows.

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    Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.

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