Features Articles - drug development, clinical trials and neuroscience

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The Last Vaccine Frontier

By Brad Spellberg | June 1, 2011

Successful vaccines have been created to protect against pathogenic bacteria and viruses. Why aren’t there any for combating fungal infections?

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Recognizing the Human Potential

By Gene M. Shearer and Adriano Boasso | June 1, 2011

It may be time to reconsider an AIDS vaccine which is more human than viral, triggering the immune system in a way that no other vaccine does.

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Shooting Down Addiction

By Thomas Kosten | June 1, 2011

A new breed of vaccines aims to wean users off cocaine.

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Taking Aim at Melanoma

By Keith T. Flaherty | April 1, 2011

Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.

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The Genes of Parkinson’s Disease

By Bobby Thomas and M. Flint Beal | February 1, 2011

The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.

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Mining Bacterial Small Molecules

By L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | January 1, 2011

As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

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