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drug development, genetics & genomics

How to Build Bioinformatic Pipelines Using Galaxy
Jeffrey M. Perkel | Aug 1, 2016 | 7 min read
A point-and-click interface alternative to command-line tools that allows researchers to easily create, run, and troubleshoot serial sequence analyses
Do Patents Promote or Stall Innovation?
Catherine Offord | Jun 1, 2016 | 10 min read
A petition recently filed with the Supreme Court triggers renewed debate about the role of patents in the diagnostics sector.
Noncoding RNAs Not So Noncoding
Ruth Williams | Jun 1, 2016 | 10+ min read
Bits of the transcriptome once believed to function as RNA molecules are in fact translated into small proteins.
First Data from Anti-Aging Gene Therapy
Kerry Grens | Apr 25, 2016 | 4 min read
A biotech company reports that an experimental treatment elongated its CEO’s telomeres. 
Family Ties
Mary Beth Aberlin | Dec 1, 2015 | 3 min read
There’s more to inheritance than genes.
Stem Cell Therapy In Utero
Kerry Grens | Oct 13, 2015 | 1 min read
An upcoming clinical trial aims to correct for a disease of fragile bones in affected babies before they are born.
Phase 3 Win for Gene Therapy
Kerry Grens | Oct 6, 2015 | 2 min read
The treatment restored sight among people with an inherited visual impairment.
Alphabet Announces Life Sciences
Tracy Vence | Aug 24, 2015 | 1 min read
Google’s parent company is launching a research-and-development project as a standalone firm.
Fending Off Infection in Future Generations
Jef Akst | Aug 17, 2015 | 2 min read
Female fruit flies challenged with infection during their lifetimes have offspring with greater genetic diversity.
Not So Noncoding
Jenny Rood | Jun 1, 2015 | 2 min read
An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.
23andMe Enters Drug Development
Kerry Grens | Mar 12, 2015 | 2 min read
The personal genomics firm announces plans to make medicines.
Genome Digest
Jenny Rood | Mar 4, 2015 | 6 min read
What researchers are learning as they sequence, map, and decode species’ genomes
Wrangling Retrotransposons
Andrei Seluanov, Michael Van Meter, and Vera Gorbunova | Mar 1, 2015 | 8 min read
These mobile genetic elements can wreak havoc on the genome. Researchers are now trying to understand how such activity contributes to the aging process.
Centennial Shigella
Jef Akst | Feb 1, 2015 | 4 min read
A strain of the dysentery-causing bacterium isolated in 1915 tells the story of a young soldier who died of the disease in the early days of World War I.
Mistaken Identities
Kerry Grens | Dec 31, 2014 | 4 min read
Researchers are working to automate the arduous task of identifying—and amending—mislabeled sequences in genetic databases.
Australian Court Upholds Patents on Human Genes
Molly Sharlach | Sep 8, 2014 | 2 min read
The Federal Court of Australia rejected an appeal of a ruling that allows companies to patent isolated human genes.
Week in Review: July 28–August 1
Tracy Vence | Aug 1, 2014 | 3 min read
See-through organs and animals; distinguishing white from brown and beige fat cells; chipping away at genetic mosaicism; catching up with the blogger behind Street Anatomy
Week in Review: June 23–27
Tracy Vence | Jun 26, 2014 | 3 min read
Tracking chikungunya virus; reconsidering wood decay-based fungal classification; ASC specks spread inflammation; antibiotic tolerance in E. coli; RIKEN review yields corrections
Singularly Alluring
Jeffrey M. Perkel | Jun 1, 2014 | 7 min read
Microfluidic tools and techniques for investigating cells, one by one
Augmenting the Genetic Alphabet
Kate Yandell | May 7, 2014 | 3 min read
For the first time, synthetic DNA base pairs are replicated within living bacteria.
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