The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
Four dozen children with severe combined immunodeficiency (SCID) who received a corrective gene carried by a virus have working immune systems two to three years later, according to three independent clinical trials.
Clinical trials were halted after the treatment’s vector that ferries in the healthy genetic sequence was identified in the genome of a patient’s cancer cells.
The Sloan Kettering researcher used mutagenic screening to probe genes and molecular pathways, including Toll and Hedgehog, essential to development in fruit flies and mice.
Services promising scientifically tailored supplements or advice abound. Experts say their claims are largely unfounded, although some solid evidence is beginning to emerge.
Breast cancer researcher and oncologist Nancy Davidson discusses what we’ve learned from the first wave of epigenetic trials for breast cancer, and what challenges lie ahead before such therapies reach the clinic.
The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.