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Top 10 Innovations 2014
The Scientist | Dec 1, 2014 | 10+ min read
The list of the year’s best new products contains both perennial winners and innovative newcomers.
Taking The Measure Of The Message
Laura De Francesco | Nov 22, 1998 | 9 min read
Date: November 23, 1998Product Comparison Getting a measure of even a single RNA species has never been easy. Every few years, a new technique comes along--Northerns, ribonuclease protection assays, RT-PCR--that makes the task only incrementally easier. But a quantum leap in technology took place just a few years ago with the introduction of cDNA arrays, and suddenly not just one but hundreds to thousands of target nucleic acids can be analyzed simultaneously and precisely. Since then, array te
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Biotech Firm Learns Hard Lessons As Its Founder Seeks To Halt Slide
Sally Lehrman | Jun 24, 1990 | 8 min read
Applied Biosystems finds that as a start-up's glamour fades, it must stress a return to basics FOSTER CITY, CALIF. - The engineer who cofounded Applied Biosystems and made it into a superstar of the biotech instruments industry, only to step back and see it stumble, is back at the helm. And Andre Marion believes that what once worked for the company is also the surest route to its future success. "Success lies in the ability to take chances," says Marion, who returned to hands-on management o
Today's Lab
Laura Defrancesco | Mar 3, 2002 | 8 min read
Tom Sargent remembers the day a student in his lab forgot to add boiling chips to phenol before firing up the heater on the distillation apparatus, and the panicked shouting and tearing off of the lab coat, goggles, gloves, and shoes that ensued when the phenol superheated and boiled over. "Fortunately he wasn't hurt," said Sargent, now chief of the section on vertebrate development at the National Institute of Child and Human Development, "but what a mess." Then, there was the time he hooked up
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
A Sharper Image
Bob Sinclair | Apr 29, 2001 | 10+ min read
Medical miracles abound, yet cancer continues to be a complex and challenging problem. "Cancer" is actually a generic, catchall term for the malignant tumors that are found in well over a hundred different diseases, but the basic concept is simple enough--a gene goes wrong and a tumor grows. Unfortunately, the reality is more complicated, involving an intricate sequence of phenomena and interactions in just a handful of the body's tens-of-trillions of cells. And therein lies the problem for rese
Beyond Sanger: Toward the $1,000 Genome
Aileen Constans | Jun 29, 2003 | 10 min read
Courtesy of Solexa Total Genotyping Without a doubt, the quarter-century-old Sanger sequencing method performed like a champ during the Human Genome Project. But with the capacity to read only a few hundred bases per reaction, it is far too slow and expensive for routine use in clinical settings. Reaping the rewards of the genomics era will clearly require faster and cheaper alternatives. Some companies estimate that within the next five years, technical advances could drop the cost of seque
Field of Dreams
Aileen Constans | Jun 25, 2000 | 10+ min read
Magnetic Separation Systems Suppliers of Magnetic Microspheres for a Variety of Applications Labsystems' KingFisher Magnetic Particle Processor plunges into the magnetic separation scene. Since LabConsumer's last profile of magnetic bead technology, the use of paramagnetic particles in biological separations and detection has exploded.1 However, development of processing technologies has lagged behind refinements of the beads themselves. The instrumentation emerging within the last few years

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