A rundown of tools on the market and in development

Quantitative real-time technology dominates the market today but digital PCR is on the rise.

A green fluorescent dye with a novel DNA binding mechanism improves signal-to-noise in different DNA amplification assays.

Enhancing data collection from emulsion PCR reactions: three case studies

Apps and software for improving lab productivity

Date: November 23, 1998Product Comparison Getting a measure of even a single RNA species has never been easy. Every few years, a new technique comes along--Northerns, ribonuclease protection assays, RT-PCR--that makes the task only incrementally easier. But a quantum leap in technology took place just a few years ago with the introduction of cDNA arrays, and suddenly not just one but hundreds to thousands of target nucleic acids can be analyzed simultaneously and precisely. Since then, array te

There is a war going on to win over the hearts and minds of molecular biologists: Radioactive isotopes-long the gold standard for tagging and later detecting RNA and DNA strands- are being challenged by a new generation of fluorescent labels that promise greater flexibility with fewer disposal problems. SEQUENCE DETECTION SYSTEM: Perkin-Elmer’s ABI Prism 7700 system uses a probe with a reporter and a quencher dye attached to it. With 14C, 32P, 125I, 3H, or some other radioactive atom bui

Researchers devise numerous strategies to encode information into nucleic acids.

Novel microfluidic devices give researchers new ways to count and sort single cells.

From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.