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Assay for Sickle Cell Anemia Is Repurposed to Diagnose COVID-19
G.B.S.N.P. Varma | Nov 18, 2020 | 5 min read
A CRISPR-based, paper-strip test developed by Indian researchers performs as well as real-time PCR in identifying the presence of SARS-CoV-2 and returns results within an hour.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Flow Cytometry On-a-Chip
Jeffrey M. Perkel | Jun 1, 2015 | 7 min read
Novel microfluidic devices give researchers new ways to count and sort single cells.
Top 10 Innovations 2014
The Scientist | Dec 1, 2014 | 10+ min read
The list of the year’s best new products contains both perennial winners and innovative newcomers.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Oligos To Go! : Purveyors of Custom Oligos
Jim Kling | Mar 29, 1998 | 7 min read
Date: March 30, 1998 Author: Jim Kling Table of Vendors So--the boss calls you into her office and tells you it's time to find another supplier of oligonucleotides. The custom house you've been using just went out of business, or maybe your team is preparing to delve into a new research project that calls for oligos. You scan the ads in several journals and do a quick internet search. Before you know it you've got a 'short' list of 50-100 suppliers. Wading through a sea of suppliers to find th
Prospecting for Gold in Genome Gulch
Amy Adams | Apr 14, 2002 | 9 min read
The human genome is much like the American West of the 1850s: Everyone wants a piece of the pie. Similar to gold prospectors of 150 years ago, biotech and pharmaceutical companies, and even universities, are frantically searching for the nuggets of gold that will help them find the mother lode—a gene whose function is sufficiently marketable to make all of the preliminary research worthwhile. Companies that do strike gold get to introduce new classes of drugs to the market. Others hope to
DNA, RNA Probes Help Investigators Narrow The Search For Genes
Holly Ahern | Nov 26, 1995 | 10+ min read
For Genes Author: Holly Ahern For a geneticist, pinpointing a mutation in a human gene that might be responsible for an inherited disease can be likened to the proverbial search for a needle in a haystack. While mo-lecular biologists sift through the 3 billion base pairs in the human genome in search of disease-causing genes, other scientists choose to approach the problem from the perspective of the mouse, a model system for mammal research. Because mice and humans are members of the same gr
Today's Lab
Laura Defrancesco | Mar 3, 2002 | 8 min read
Tom Sargent remembers the day a student in his lab forgot to add boiling chips to phenol before firing up the heater on the distillation apparatus, and the panicked shouting and tearing off of the lab coat, goggles, gloves, and shoes that ensued when the phenol superheated and boiled over. "Fortunately he wasn't hurt," said Sargent, now chief of the section on vertebrate development at the National Institute of Child and Human Development, "but what a mess." Then, there was the time he hooked up
Nanotech Dreams
Jeffrey Perkel | Mar 3, 2002 | 9 min read
Nanotechnology hit the big time in July 1995, when it debuted on the television show, The Outer Limits. In an episode entitled "The New Breed," a scientist develops nanorobots capable of repairing damaged cells and correcting physical defects. But, like any good morality play, the experiment goes horribly wrong, turning a panacea into a nightmare. Clearly, nanotechnology makes for good science fiction, but scientists have been working to make it an interesting reality, too. Nanotechnology refers

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