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tag techniques epigenetics disease medicine immunology

T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
diabetes complications type 2 biomarker blood test screen hydroxymethylation epigenetics cytosine
Blood-Based Epigenetic Screen Tests for Diabetes Complications
Katarina Zimmer | Oct 1, 2019 | 4 min read
Researchers could accurately detect life-threatening vascular complications in type 2 diabetes patients by analyzing hydroxymethylated cytosines in freely circulating DNA.
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Underlying Pathways: The Key to Progress in Rheumatology?
Janssen Immunology | Nov 17, 2021 | 4 min read
Understanding immune pathways and disease mechanisms helps address the unmet needs of patients living with difficult-to-treat rheumatic diseases.
Unmasking Secret Identities
Kate Yandell | Feb 1, 2014 | 9 min read
A tour of techniques for measuring DNA hydroxymethylation
lab tools cancer therapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019 | 7 min read
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
Pinpointing the Culprit
Rachel Berkowitz | Jun 1, 2017 | 8 min read
Identifying immune cell subsets with CyTOF
3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.

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