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tag epigenetics physiology culture disease medicine

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
Medical illustration depicting self-renewal of a single stem cell dividing into two identical cells.<br><br>
What Is Stemness and Pluripotency?
Deanna MacNeil, PhD | Sep 30, 2022 | 5 min read
Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery.
Epigenetics of Trained Innate Immunity
Ruth Williams | Sep 25, 2014 | 3 min read
Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018 | 10 min read
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.
How Muscles Age, and How Exercise Can Slow It
Gillian Butler-Browne, Vincent Mouly, Anne Bigot, and Capucine Trollet | Sep 1, 2018 | 10+ min read
Researchers untangle the multifarious nature of muscle aging. So far, the only reliable treatment is exercise.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Leaving an Imprint
Anna Azvolinsky | Aug 1, 2015 | 8 min read
Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

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