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Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications

The methodology involves modifying histones and displaying them on the cell surface for analysis.

The methodology involves modifying histones and displaying them on the cell surface for analysis.

epigenetics, cell & molecular biology

Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Advances in Nucleic Acid Sequencing
The Scientist | 1 min read
Download this eBook to learn how new sequencing methods revolutionize genetics research!
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020 | 5 min read
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
Q&A: How Animals Change in Space
Jef Akst | Nov 25, 2020 | 4 min read
Weill Cornell Medicine geneticist Christopher Mason speaks with The Scientist about a bolus of new work on the physiological, cellular, and molecular effects of leaving Earth.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019 | 3 min read
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
Ribosomal DNA Can Predict an Animal’s Age
Abby Olena, PhD | Feb 14, 2019 | 3 min read
A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019 | 7 min read
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
RNA Moves a Memory From One Snail to Another
Ashley Yeager | May 14, 2018 | 4 min read
Injecting molecules from a sea slug that received tail shocks into one that didn’t made the recipient animal behave more cautiously. 
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017 | 10+ min read
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
New Epigenetic Mark Confirmed in Mammals
Jef Akst | Apr 1, 2016 | 2 min read
Methylation on adenine bases is involved in the dampening of gene expression in mammalian cells, according to a study.
Aging Shrinks Chromosomes
Ruth Williams | Feb 5, 2016 | 3 min read
A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.
Messages in the Noise
Sarah C.P. Williams | Aug 1, 2015 | 7 min read
After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.
Leaving an Imprint
Anna Azvolinsky | Aug 1, 2015 | 8 min read
Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.
Mr. Epigenetics
The Scientist | Jul 31, 2015 | 1 min read
Meet Wolf Reik, August Profilee and Babraham Institute director of research.
Extra DNA Base Discovered
Jef Akst | Jun 23, 2015 | 1 min read
An epigenetic variant of cytosine is stable in the genomes of living mice, suggesting a possible expansion of the DNA alphabet.
From Many, One
Elena E. Giorgi | Apr 1, 2015 | 10+ min read
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?
Weiwei Dang: Epigenetics in Aging
Jef Akst | Mar 1, 2015 | 3 min read
Assistant Professor, Huffington Center On Aging, Baylor College of Medicine. Age: 38
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