immunology, infectious disease

Timely modulation of a common signaling pathway can preserve influenza memory in lung T cells.

A host lipid-modifying enzyme plays a key role in HIV envelope formation, viral maturation, and infectivity. 

Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education.

The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.

Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.

The bacterium produces a particular protein that allows it to sneak past the human immune system even while triggering inflammation.

Chlamydia trachomatis, the bacterium that causes chlamydia, hides from the immune system by cloaking itself in the host cell’s membrane then modifying the membrane’s protein composition.

The “tripledemic” shines a spotlight on viral interference, in which one infection can block another.

Warm nasal cells mount stronger defenses against cold-causing coronaviruses and rhinoviruses than those exposed to cooler temperatures, an in vitro experiment finds.

A clinical trial finds that the anticoagulant apixaban, which has been prescribed to help COVID-19 patients recover, is ineffective and in rare instances dangerous.

Bats are known for staying healthy even while harboring viral infections. Now, research sheds light on how their unusual immune system evolved.

He also worked on immunizations against polio, rubella, influenza, and more.

It’s not clear why grain-fed mice are better able to recover after infection, but a study’s findings suggest food type may skew the results of animal studies.