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tag mutations bone growth limb development human evolution

A Simple Genetic Change Adds Limb-Like Bones to Zebrafish Fins
Abby Olena, PhD | Feb 5, 2021 | 4 min read
A gain-of-function mutation in a single gene reveals ancient limb-forming capacity that has been preserved for hundreds of millions of years.
Animalsā€™ Embryonic Organizer Now Discovered in Human Cells
Jim Daley | May 23, 2018 | 4 min read
The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.
Bite makes way for brain
Brendan Maher(bmaher@the-scientist.com) | Mar 23, 2004 | 4 min read
A single mutation may have caused gross anatomical changes that spurred human evolution
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Decoding Human Accelerated Regions
Katherine S. Pollard | Aug 1, 2016 | 10 min read
Do the portions of our genomes that set us apart from other animals hold the secret to human evolution?
giraffe, genetics & genomics, CRISPR, gene editing, genome, physiology, hypertension, bone growth, techniques, mouse model
Genome Reveals Clues to Giraffes’ “Blatantly Strange” Body Shape
Amanda Heidt | Mar 19, 2021 | 5 min read
The physiological demands of that long neck get support from a gene involved in strengthening bones and blood vessels, researchers find after inserting the sequence in mice.
Down to the bone
Elie Dolgin | Jun 28, 2009 | 3 min read
A fusion protein that ferries a healthy version of a bone-related enzyme gone awry has shown early clinical success in treating a rare bone disorder with no known therapy, researchers reported earlier this month at the Endocrine Society's linkurl:annual meeting;http://www.endo-society.org/endo/ in Washington, DC. The drug -- which is essentially a protein-based enzyme delivery mechanism -- could open the door to treatments of other skeletal disorders that have so far been deemed untreatable. Ra
a purple betta with white fins in a tank
My Daughter’s First Pet—the Next Big Model Organism?
Christie Wilcox, PhD | Jul 15, 2021 | 10+ min read
Bettas were likely the first fish welcomed into human homes. Now, scientists are welcoming them into the lab to learn how genes dictate their appearance and behavior.
Macrophages Are the Ultimate Multitaskers
Claire Asher | Oct 1, 2017 | 10+ min read
From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.

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