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tag mutations bone growth epigenetics neuroscience

Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Immune Role in Brain Disorder?
Hannah Waters | Mar 19, 2012 | 3 min read
Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.
Making Neurons
Cynthia Fox | Sep 17, 2000 | 9 min read
Image courtesy of Eyewire ©2000, Graphic: Cathleen Heard How do you make a neuron? Nowadays, that depends on how you like your neurons. Perhaps you're having problems expanding your neural stem cells (NSCs) to large numbers because after repeated passaging, they lose the phenotype or go into crisis. Read the June Nature Biotechnology, where National Institute of Neurological Disorders and Stroke neurobiologist Ron McKay offers a recipe for making dopaminergic and GABAnergic neurons from rat
The Four R's
Amy Norton | Nov 21, 2004 | 7 min read
Teams at each of New York City's leading universities are making important research advances.
Debate Over Stem Cell Origins Continues
Ricki Lewis | May 26, 2002 | 7 min read
In science, things are not always as they seem. So it is for transdifferentiation, the apparent interconvertibility of certain specialized cell types and an underlying theme at a symposium on stem cell biology and applications at the recent annual meeting of the American Association for Cancer Research (AACR) in San Francisco. "For the past three years, people have been saying that hematopoietic [blood-forming] stem cells can become just about any tissue, challenging the paradigm that there are
How Well Do Mice Model Humans?
Ricki Lewis | Oct 25, 1998 | 8 min read
STRIKING RESEMBLANCE: James Croom, who studies Down syndrome mice at North Carolina State University, says the animals are providing valuable information useful to humans. When a page-one article in the May 3, 1998, Sunday New York Times portrayed angiogenesis inhibitors that fight cancer in mice as being possible just around the corner for humans, criticism for raising false hopes erupted. Merely 10 weeks later, however, when researchers from the University of Hawaii reported cloning the fi
Applications Of Image Analysis Systems Expand Beyond The Research Lab
Ricki Lewis | Oct 27, 1996 | 10+ min read
TIME EFFICIENT: The AMBIS radioisotopic imager from Scanalytics/CSPI. Already an invaluable tool in some basic research, image analysis is edging into the classroom and the clinic. "Any field of life science that can put a video camera onto a microscope will begin to use image analysis," predicts Richard Cardullo, an associate professor of biology at the University of California, Riverside. In general, the technique acquires, digitizes, and then processes a microscope or scanned image, enhan

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