With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

A snapshot of the most highly ranked articles in evolutionary biology and related areas, from Faculty of 1000

After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.

Did behaviors that seem ingrained become fixed through epigenetic mechanisms and ancestral learning?

Jumping genes in bdelloid rotifers are tamped down by DNA methylation performed by an enzyme pilfered from bacteria roughly 60 million years ago, a study finds.

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

The concept of epigenetic inheritance has long been controversial. Some researchers hope that new data on cross-generational effects of environmental exposures will help settle the debate.

George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

The African Ancestry Neuroscience Research Initiative plans to boost inclusion in genomic studies and support a more diverse generation of neuroscientists.