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tag limb development bone growth mutations disease medicine

Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Homing Technology Delivers Therapy to Cancerous Bone
Roni Dengler, PhD | Jul 19, 2021 | 5 min read
A clever approach to modifying already existing cancer therapies may be a game changer for treating metastatic breast cancer.
Defining Rare Disorders: A Profile of Judith Hall
Anna Azvolinsky | Sep 1, 2019 | 8 min read
By bringing genetics into clinical medicine, the University of British Columbia medical geneticist helped to identify the gene mutations responsible for many rare diseases.
Down to the bone
Elie Dolgin | Jun 28, 2009 | 3 min read
A fusion protein that ferries a healthy version of a bone-related enzyme gone awry has shown early clinical success in treating a rare bone disorder with no known therapy, researchers reported earlier this month at the Endocrine Society's linkurl:annual meeting;http://www.endo-society.org/endo/ in Washington, DC. The drug -- which is essentially a protein-based enzyme delivery mechanism -- could open the door to treatments of other skeletal disorders that have so far been deemed untreatable. Ra
Telomeres in Disease
Rodrigo Calado and Neal Young | May 1, 2012 | 10+ min read
Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.
Macrophages Are the Ultimate Multitaskers
Claire Asher | Oct 1, 2017 | 10+ min read
From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.
Animals’ Embryonic Organizer Now Discovered in Human Cells
Jim Daley | May 23, 2018 | 4 min read
The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.
Pulling It All Together
Kate Yandell | Apr 1, 2016 | 9 min read
Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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