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tag limb development science publishing mutations developmental biology evolution

One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Wild water striders (Microvelia longipes) on a puddle. The animals with long third legs are the males; the others are females.
A Multipurpose Gene Facilitates the Evolution of an Animal Weapon
Viviane Callier | May 11, 2021 | 4 min read
A single gene called BMP11 regulates not only the size and proportions of a water strider’s massively long third legs, but also how it uses the limbs in fights.
Animalsā€™ Embryonic Organizer Now Discovered in Human Cells
Jim Daley | May 23, 2018 | 4 min read
The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.
Close up view of fruit fly
Science Snapshot: Here’s Lookin’ At You, Kid
Lisa Winter | Apr 13, 2022 | 1 min read
Experimentally nudging the patterning within the compound eyes of insects.
Green-tinged image of fly eye with shiny and black portions
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
Jason P. Dinh | Jul 1, 2022 | 4 min read
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
A Cape ground squirrel sits upright on its hind legs, holding its forelimbs up to its face.
Animals Are Shape-Shifting in Response to a Warming World
Andy Carstens | Jan 3, 2023 | 10 min read
Forced to respond to a climate that’s changing faster than it ever has, it remains unclear whether species’ adaptations can keep pace.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Genetics Models Move Beyond Drosophila and the Humble Lab Mouse
Amber Dance | Sep 1, 2019 | 8 min read
Organisms with unusual genomes are helping scientists investigate gene regulation, evolution, and development.

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