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stem cells, mutations

234-Year-Old Tree Has Impressively Stable Genome
Jef Akst | Jun 20, 2017 | 1 min read
Genomic analysis of an oak tree that lived during Napoleon’s time supports the idea that plants somehow avoid the accumulation of mutations in their stem cells.
Cell Lines Gain Cancer-Related Mutations
Kerry Grens | Apr 27, 2017 | 1 min read
A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.
Gene Therapy Coming of Age?
Dan Cossins | Jul 11, 2013 | 4 min read
Using lentiviral vectors to replace mutated genes in blood stem cells, scientists successfully treat two rare diseases apparently without causing harmful side effects.
First, Do No Harmā€¦
Jim Woodgett | Jun 9, 2011 | 5 min read
Is DNA damage an inevitable consequence of epigenetic reprogramming?
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