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tag stem cells epigenetics neuroscience behavior

early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
c elegans transgenerational epigenetic inheritance behavior neuron genetics
Worm Parents Pass on Behaviors Epigenetically to Offspring
Katarina Zimmer | Jun 7, 2019 | 7 min read
Two research groups demonstrate that in Caenorhabditis elegans, behavioral traits can be passed down through the germline to future generations, even though they aren’t hard-wired.
Nerve cell labelled with different colours
Psychedelics Slip Past Cell Membranes When Treating Depression
Alejandra Manjarrez, PhD | Feb 24, 2023 | 4 min read
The antidepressant properties of hallucinogenic drugs may stem from their ability to bind to intracellular serotonin receptors, a study suggests.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
A pair of prairie voles (Microtus ochrogaster)
Monogamous Rodents Don’t Need “Love Molecule” To Pair Up
Natalia Mesa, PhD | Jan 27, 2023 | 4 min read
Prairie voles lacking functional receptors for oxytocin form normal social bonds, a finding that could explain the hormone’s clinical failures.
Advancing Techniques Reveal the Brain’s Impressive Diversity
Sara B. Linker, Fred H. Gage, and Tracy A. Bedrosian | Nov 1, 2017 | 10+ min read
No two neurons are alike. What does that mean for brain function?
Distinct methylation in stem cell DNA
Charles Choi | Aug 6, 2006 | 3 min read
Findings may help explain why embryonic stem cells can self-renew and are pluripotent
Week in Review: May 5–9
Tracy Vence | May 8, 2014 | 4 min read
Synthetic base pairs replicated in vivo; cardiac stem cells questioned; miniature neurotransmissions and synaptic development; neurogenesis and memory loss; STAP saga continues
Debate Over Stem Cell Origins Continues
Ricki Lewis | May 26, 2002 | 7 min read
In science, things are not always as they seem. So it is for transdifferentiation, the apparent interconvertibility of certain specialized cell types and an underlying theme at a symposium on stem cell biology and applications at the recent annual meeting of the American Association for Cancer Research (AACR) in San Francisco. "For the past three years, people have been saying that hematopoietic [blood-forming] stem cells can become just about any tissue, challenging the paradigm that there are
Brain cells with electrical firing. 3D rendering.
Microglia as Therapeutic Targets in Neurodegenerative Diseases
Sruthi S. Balakrishnan | Oct 1, 2021 | 10+ min read
Pharmaceutical companies ramp up efforts to get the brain’s immune cells to help treat Alzheimer’s disease and other conditions, but not everyone agrees the approach will be effective.

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