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tag stem cells epigenetics techniques limb development
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Advanced Spatial Tools Map Hematopoietic Stem Cell Niches
Niki Spahich, PhD
| Jan 15, 2024
| 4 min read
New technologies and archival tissue biopsy samples enable exploration of changes in the bone marrow as people age.
Alcohol Leaves its Mark on Immune Cells
Shelby Bradford, PhD
| Jan 1, 2024
| 2 min read
The immune system's recovery from chronic alcohol use could take longer than some rehabilitation periods due to alcohol's effects on stem cells.
Differentiated Stem Cells Can Kickstart Fertility in Mice
Aparna Nathan, PhD
| Oct 23, 2023
| 3 min read
Ovarian cells derived from stem cells restore hormones and cells needed to produce pups.
Oocytes direct from embryonic stem cells
Cathy Holding(cholding@hgmp.mrc.ac.uk)
| May 1, 2003
| 2 min read
Novel cloning technique sidesteps problems associated with epigenetic imprints.
Image of the Day: Beating Heart
Sukanya Charuchandra
| Jul 2, 2018
| 1 min read
Scientists at the Allen Institute for Cell Science have developed an open-source stem cell line with fluorescent tags for cardiac cells.
Stem Cells Made by Modifying the Epigenome with CRISPR
Abby Olena, PhD
| Jan 25, 2018
| 3 min read
Researchers use the technique to turn on
Oct4
or
Sox2
in mouse embryonic fibroblasts and convert them into pluripotent cells.
Pluripotent Until Needed
Beth Marie Mole
| Apr 1, 2013
| 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving
| Feb 17, 2023
| 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
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