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tag stem cells epigenetics limb development dna methylation evolution

a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
RNA Epigenetics
Gidi Rechavi, Chuan He, and Dan Dominissini | Jan 1, 2016 | 10 min read
DNA isn’t the only decorated nucleic acid in the cell. Modifications to RNA molecules are much more common and are critical for regulating diverse biological processes.
High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018 | 7 min read
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
A Long Line of LINEs
Kate Yandell | Sep 1, 2014 | 3 min read
Different mechanisms repress mobile DNA elements in human embryonic stem cells depending on the elements’ evolutionary ages.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Epigenetics—A Primer
Stefan Kubicek | Mar 1, 2011 | 1 min read
There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019 | 7 min read
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017 | 10+ min read
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Pluripotent Until Needed
Beth Marie Mole | Apr 1, 2013 | 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
Human DNA abstract dotwork vector illustration made of cloud of colored dots.
Adapting with a Little Help from Jumping Genes
Christie Wilcox, PhD | Jan 17, 2022 | 10+ min read
Long lambasted as junk DNA or genomic parasites, transposable elements turn out to be contributors to adaptation.

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