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tag stem cells epigenetics limb development disease medicine physiology

Medical illustration depicting self-renewal of a single stem cell dividing into two identical cells.<br><br>
What Is Stemness and Pluripotency?
Deanna MacNeil, PhD | Sep 30, 2022 | 5 min read
Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery.
A younger-looking mouse next to an older-looking one
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
Woman smiling at the camera working out on a blue yoga mat.
Keeping Older Muscles Strong
Hannah Thomasy, PhD, Drug Discovery News | Sep 5, 2023 | 5 min read
From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
RNA Epigenetics
Gidi Rechavi, Chuan He, and Dan Dominissini | Jan 1, 2016 | 10 min read
DNA isn’t the only decorated nucleic acid in the cell. Modifications to RNA molecules are much more common and are critical for regulating diverse biological processes.
a spiny mouse sits on a piece of wood holding a small morsel to its mouth
Spiny Mice Appear to Regenerate Damaged Kidneys
Dan Robitzski | Nov 3, 2021 | 5 min read
The mice, already known to regenerate skin, seem to avoid the tissue scarring that leads to organ failure in other animals.
Synthego Launches High Throughput Induced Pluripotent Stem Cell Genome Engineering
Synthego | Oct 29, 2019 | 2 min read
National Institutes of Health awards contract for CRISPR-based disease modeling in iPS cell lines associated with Alzheimer’s, Stem cell pioneer Bill Skarnes joins advisory board
Illustration showing the upper part of a human body connected to a DNA helix
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 

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