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tag disease medicine dna methylation stem cells limb development human evolution
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving
| Feb 17, 2023
| 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Jumping Genes’ Role in Cancer
Diana Kwon
| Mar 1, 2023
| 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Aging-Related Diseases May Be a Negative Outcome of Human Evolution
Sukanya Charuchandra
| May 31, 2018
| 3 min read
Genetic adaptations for human brain development also make us vulnerable to Alzheimer’s disease, according to a new study.
Spiny Mice Appear to Regenerate Damaged Kidneys
Dan Robitzski
| Nov 3, 2021
| 5 min read
The mice, already known to regenerate skin, seem to avoid the tissue scarring that leads to organ failure in other animals.
Week in Review: February 23–27
Tracy Vence
| Feb 27, 2015
| 3 min read
Stem cells in culture; engineered cancer biomarkers; small molecule improves stem cell homing; reproducible bacterial evolution; how human adaptive immunity develops
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD
| Dec 4, 2023
| 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Bespoke Stem Cells for Brain Disease
Nsikan Akpan
| Jan 14, 2013
| 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.
The Role of DNA Base Modifications
Skirmantas Kriaucionis
| Sep 1, 2017
| 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
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