In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.

Mice appear to pass certain fears onto their offspring, according to a new study.

The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.

A wiring map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.

No two neurons are alike. What does that mean for brain function?

Courtesy of Genevieve Anderson If not for Nobel laureates Thomas Hunt Morgan, Eric R. Kandel, and Sydney Brenner, the notion of a general behavioral model might seem odd. Behaviors, after all, are determined by an animal's evolutionary history and ecological niche. They are often idiosyncratic, shared in detail only by closely related species. But, thanks to Morgan's research in the early 20th century, and Kandel's and Brenner's work over the past 35 years, the fly Drosophila melanogaster, t

Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.