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tag epigenetics stem cells bone growth developmental biology

3D rendered single cell next to a cluster of cells, illustrating the concept of stem cell differentiation and proliferation.
Selecting Cytokines for Organoid Cultures
The Scientist Staff | Mar 1, 2024 | 2 min read
Scientists optimize organoid culture growth and consistency with validated growth factor panels.
Epigenetics of Embryonic Stem Cells
Kate Yandell | May 14, 2013 | 2 min read
Researchers track DNA modifications and gene expression in stem cells as they differentiate.
Top 7 in developmental biology
Bob Grant | Oct 4, 2010 | 3 min read
Check out the hottest papers in developmental biology and related fields, as ranked by F1000
Top 7 in Developmental Biology
Edyta Zielinska | Jul 12, 2011 | 3 min read
A snapshot of the most highly ranked articles in developmental biology and related areas, from Faculty of 1000.
Stem Cell Sculpting
Jack Lucentini | Aug 29, 2004 | 3 min read
SHAPING A COMMITMENT:© 2004 Cell PressBrightfield images of hMSCs plated onto small 1,024 μm2 or large 10,000 μm2 fibronectin islands after 1 week in growth or mixed media. Lipids stain red, alkaline phosphatase stains blue. Scale bar = 50 μm. (From R. McBeath et al., Dev Cell, 6:483–95, 2004)Researchers have tried for years to make stem cells differentiate into specific cell types. This work usually involves bathing the cells in molecular signals that affect their fate
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
New Workhorses of Stem Cell Technology
Ricki Lewis | Jan 21, 2001 | 5 min read
Most media reports on stem cell biology trace the field's origin to two key papers published in 1981.1,2 But Leroy Stevens at the Jackson Laboratory in Bar Harbor, Maine, laid the groundwork in mice from the 1950s through the 1970s, manipulating bizarre growths called embryoid bodies,3 to see what these cells would become. Embryoid bodies formed when cancer cells were transplanted into mouse abdomens. At first they appeared to be a ring of cells enclosing blood, debris, and a few unspecialized c
Immune Cell–Stem Cell Cooperation
Sarthak Sinha, Jeff Biernaskie, and Waleed Rahmani | Jul 1, 2016 | 10+ min read
Understanding interactions between the immune system and stem cells could pave the way for successful stem cell–based regenerative therapies.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

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