By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.
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With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
Gregory Hannon believes in taking risks—an approach that’s enabled him to make exciting new discoveries in the world of small RNAs.
While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.
First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.
Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
For Michael Dickinson, Drosophila are more than winged gene holders—they’re sophisticated systems for translating sensory information into flight instructions.
With persistence and pluck, Leslie Vosshall managed to snatch insect odorant receptors from the jaws of experimental defeat.
With strong foundations in both art and science, Ahna Skop has been able to capture the marvel of—and mechanisms behind—cytokinesis.
Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.
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