When molecular biology methods failed her, Sangeeta Bhatia turned to engineering and microfabrication to build a liver from scratch.
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By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.
Gregory Hannon believes in taking risks—an approach that’s enabled him to make exciting new discoveries in the world of small RNAs.
First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.
Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
Inspired by Darwin, Mohamed Noor has uncovered the molecular dance by which a single species becomes two.
Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.
Joy Ward is reaping the rewards of her studies on how plants handle global climate change—gathering academic accolades and presidential embraces along the way.
Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.
Her doctoral advisor told her to amuse herself, and Fiona Watt has done just that—probing individual stem cells and determining the genes and molecules that direct them to differentiate or cause them to contribute to cancer.
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