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Leaving an Imprint

By | August 1, 2015

Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.

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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.


image: All Systems Go

All Systems Go

By | December 1, 2014

Alan Aderem earned his PhD while under house arrest for protesting apartheid in South Africa. His early political involvement has guided his scientific focus, encouraging fellow systems biologists to study immunology and infectious diseases.


image: Crossing Boundaries

Crossing Boundaries

By | September 1, 2014

A groundbreaker in the study of Listeria monocytogenes, Pascale Cossart continues to build her research tool kit to understand how to fight such intracellular human pathogens.


image: Commander of an Immune Flotilla

Commander of an Immune Flotilla

By | April 1, 2014

With much of his early career dictated by US Navy interests, Carl June drew inspiration from malaria, bone marrow transplantation, and HIV in his roundabout path to a breakthrough in cancer immunotherapy.

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image: Meiosis Maven

Meiosis Maven

By | February 1, 2014

Fueled by her love of visual data and addicted to chromosomes, Abby Dernburg continues to study how homologous chromosomes find each other during gamete formation.

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Master of Fate

By | July 1, 2013

While tracing the tricky and sometimes surprising paths of multipotent cells in the skin, mammary gland, and heart, Cédric Blanpain has repeatedly turned the stem cell field on its head.  


image: The Organist

The Organist

By | May 1, 2013

When molecular biology methods failed her, Sangeeta Bhatia turned to engineering and microfabrication to build a liver from scratch.


image: Up, Up, and Array

Up, Up, and Array

By | April 1, 2013

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

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image: Immune to Failure

Immune to Failure

By | February 1, 2013

With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.



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