When molecular biology methods failed her, Sangeeta Bhatia turned to engineering and microfabrication to build a liver from scratch.
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By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.
Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
For Michael Dickinson, Drosophila are more than winged gene holders—they’re sophisticated systems for translating sensory information into flight instructions.
In pondering genome structure and function, evolutionary geneticist Laurence Hurst has arrived at some unanticipated conclusions about how natural selection has molded our DNA.
Inspired by Darwin, Mohamed Noor has uncovered the molecular dance by which a single species becomes two.
Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.
Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.
Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.
Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.
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