With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
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Gregory Hannon believes in taking risks—an approach that’s enabled him to make exciting new discoveries in the world of small RNAs.
Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
With persistence and pluck, Leslie Vosshall managed to snatch insect odorant receptors from the jaws of experimental defeat.
With strong foundations in both art and science, Ahna Skop has been able to capture the marvel of—and mechanisms behind—cytokinesis.
Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.
Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.
Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.
Ron Kaback didn’t believe that electrochemical gradients could power the transport of sugars and amino acids across cell membranes—until he proved that they do.
Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.
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