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image: All Systems Go

All Systems Go

By | December 1, 2014

Alan Aderem earned his PhD while under house arrest for protesting apartheid in South Africa. His early political involvement has guided his scientific focus, encouraging fellow systems biologists to study immunology and infectious diseases.


image: Commander of an Immune Flotilla

Commander of an Immune Flotilla

By | April 1, 2014

With much of his early career dictated by US Navy interests, Carl June drew inspiration from malaria, bone marrow transplantation, and HIV in his roundabout path to a breakthrough in cancer immunotherapy.

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image: Master of Fate

Master of Fate

By | July 1, 2013

While tracing the tricky and sometimes surprising paths of multipotent cells in the skin, mammary gland, and heart, Cédric Blanpain has repeatedly turned the stem cell field on its head.  


image: Immune to Failure

Immune to Failure

By | February 1, 2013

With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.


image: (Re)Programming Director

(Re)Programming Director

By | October 1, 2012

Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.


image: Beyond Expectation

Beyond Expectation

By | September 1, 2011

Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.


image: Foresight


By | July 1, 2011

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.


Ready, Reset, Go

By | March 1, 2011

Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.


image: Watt Fun!

Watt Fun!

By | January 1, 2011

Her doctoral advisor told her to amuse herself, and Fiona Watt has done just that—probing individual stem cells and determining the genes and molecules that direct them to differentiate or cause them to contribute to cancer.



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