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Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: All Systems Go

All Systems Go

By | December 1, 2014

Alan Aderem earned his PhD while under house arrest for protesting apartheid in South Africa. His early political involvement has guided his scientific focus, encouraging fellow systems biologists to study immunology and infectious diseases.

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image: Commander of an Immune Flotilla

Commander of an Immune Flotilla

By | April 1, 2014

With much of his early career dictated by US Navy interests, Carl June drew inspiration from malaria, bone marrow transplantation, and HIV in his roundabout path to a breakthrough in cancer immunotherapy.

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Master of Fate

By | July 1, 2013

While tracing the tricky and sometimes surprising paths of multipotent cells in the skin, mammary gland, and heart, Cédric Blanpain has repeatedly turned the stem cell field on its head.  

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image: The Organist

The Organist

By | May 1, 2013

When molecular biology methods failed her, Sangeeta Bhatia turned to engineering and microfabrication to build a liver from scratch.

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image: Up, Up, and Array

Up, Up, and Array

By | April 1, 2013

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

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image: Immune to Failure

Immune to Failure

By | February 1, 2013

With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.

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image: (Re)Programming Director

(Re)Programming Director

By | October 1, 2012

Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.

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High-Tech Choir Master

By | January 1, 2012

Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.

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image: Beyond Expectation

Beyond Expectation

By | September 1, 2011

Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.

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