With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
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Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
In exploring how embryos take shape, John Wallingford has identified a key pathway involved in vertebrate development—and human disease.
For Michael Dickinson, Drosophila are more than winged gene holders—they’re sophisticated systems for translating sensory information into flight instructions.
With persistence and pluck, Leslie Vosshall managed to snatch insect odorant receptors from the jaws of experimental defeat.
In pondering genome structure and function, evolutionary geneticist Laurence Hurst has arrived at some unanticipated conclusions about how natural selection has molded our DNA.
Inspired by Darwin, Mohamed Noor has uncovered the molecular dance by which a single species becomes two.
Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.
Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.
Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.
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