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Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.


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Master of Fate

By | July 1, 2013

While tracing the tricky and sometimes surprising paths of multipotent cells in the skin, mammary gland, and heart, Cédric Blanpain has repeatedly turned the stem cell field on its head.  


image: The Organist

The Organist

By | May 1, 2013

When molecular biology methods failed her, Sangeeta Bhatia turned to engineering and microfabrication to build a liver from scratch.


image: Up, Up, and Array

Up, Up, and Array

By | April 1, 2013

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

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image: The Road Less Traveled

The Road Less Traveled

By | November 1, 2012

First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.

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(Re)Programming Director

By | October 1, 2012

Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.


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Burgers and Flies

By | May 1, 2012

Inspired by Darwin, Mohamed Noor has uncovered the molecular dance by which a single species becomes two.


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High-Tech Choir Master

By | January 1, 2012

Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.


Ready, Reset, Go

By | March 1, 2011

Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.


image: Watt Fun!

Watt Fun!

By | January 1, 2011

Her doctoral advisor told her to amuse herself, and Fiona Watt has done just that—probing individual stem cells and determining the genes and molecules that direct them to differentiate or cause them to contribute to cancer.


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