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Caenorhabditis elegans, a free-living transparent nematode (roundworm), about 1 mm in length.
The Body, Not the Brain, Regulates Sleep
Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?
The Body, Not the Brain, Regulates Sleep
The Body, Not the Brain, Regulates Sleep

Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?

Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?

C. elegans, neuroscience

Histological stain of motor neurons in purple and green
Researchers Use Ultrasound to Control Neurons in Mice
Natalia Mesa, PhD | Feb 9, 2022 | 4 min read
A study shows “sonogenetics” could be a useful new tool in neuroscience and other fields.
Can Single Cells Learn?
Catherine Offord | May 1, 2021 | 10+ min read
A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.
a close-up photo of C. elegans worms
Eyeless C. elegans Perceives Colors: Study
Shawna Williams | Mar 4, 2021 | 4 min read
The roundworm uses cues from visible light to help avoid eating toxic bacteria with a distinguishing hue.
Daniel Colón-Ramos Reveals the Mysteries of Worms’ Memories
Claudia Lopez-Lloreda | May 1, 2020 | 3 min read
The Yale neuroscientist seeks to understand the brain’s architecture and function using C. elegans.
c. elegans sleep microfluidics
Microfluidic Chambers Trigger Sleep in C. elegans
Alejandra Manjarrez, PhD | Nov 19, 2019 | 4 min read
This newly described behavior occurs spontaneously, but can be modulated by food availability, temperature, and the size of the chambers.
How One Neuron Regulates Two Separate Behaviors
Ruth Williams | Nov 14, 2019 | 3 min read
A major sensory neuron in roundworms distinguishes proprioception from harmful touch by sending out local or whole-cell signals, respectively.
c Caenorhabditis elegans neural map neuron pathway connections connectome
Biologists Create New Maps of Caenorhabditis elegans Neurons
Chia-Yi Hou | Jul 8, 2019 | 2 min read
The connectomes trace 385 neurons in the male worm and 302 neurons in the hermaphrodite worm.
c elegans transgenerational epigenetic inheritance behavior neuron genetics
Worm Parents Pass on Behaviors Epigenetically to Offspring
Katarina Zimmer | Jun 7, 2019 | 7 min read
Two research groups demonstrate that in Caenorhabditis elegans, behavioral traits can be passed down through the germline to future generations, even though they aren’t hard-wired.
Worms’ Magnetic Sense Questioned
Abby Olena, PhD | Apr 25, 2018 | 5 min read
Unsuccessful attempts to reproduce the results of a 2015 study reporting that C. elegans orient themselves by Earth’s magnetic field spark debate among researchers.
How Roundworms Sleep
Diana Kwon | Jun 22, 2017 | 3 min read
When Caenorhabditis elegans surrenders to slumber, the majority of its neurons fall silent.
Newfound Neurons
Tracy Vence | Oct 19, 2015 | 1 min read
Researchers identify a new type of brain cell in male Caenorhabditis elegans.
Filming the Nematode Brain
Jef Akst | Jan 26, 2015 | 1 min read
Researchers record the first whole-brain videos of an unrestrained animal, viewing neural activity as a roundworm moved freely around a Petri dish.
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