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tag cancer cell molecular biology structural biology neuroscience

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Molecular Biology
The Scientist Staff | Oct 27, 1991 | 2 min read
S.J. Rhodes, S.F. Konieczny, "Identification of MRF4: a new member of the muscle regulatory factor gene family," Genes & Development, 3:2050-61, 1989. Stephen F. Konieczny (Purdue University, West Lafayette, Ind.): "This paper describes the identification and characterization of MRF4, the fourth member of a structurally and functionally related family of muscle regulatory factors that includes MyoD, myogenin, and Myf-5. Forced expression of MRF4 in fibroblasts converts nonmuscle cells to skele
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
S. Hahn, S. Buratowski, P.A. Sharp, L. Guarente, "Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions," Cell, 58, 1173-81, 22 September 1989. Steven Hahn (Fred Hutchinson Cancer Research Center, Seattle): "TFIID is one of the essential components in the machinery necessary to initiate transcription by RNA polymerase II. For eight years after the discovery of TFIID in mammals, little was known about it because of
MOLECULAR BIOLOGY
The Scientist Staff | Dec 8, 1991 | 2 min read
MOLECULAR BIOLOGY Date: December 9, 1991 D. Anderson, C.A. Koch, L. Grey, C. Ellis, et al., "Binding of SH2 domains of phospholipase Cg1, GAP, and Src to activated growth factor receptors," Science, 250:979-82, 1990. Tony Pawson (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto): "Many of the hormones that control cell growth, differentiation, and metabolism in the adult, and development in the embryo, bind to the extracellular region of receptors that span th
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Cell Biology
The Scientist Staff | Oct 25, 1992 | 1 min read
J. Martin, T. Langer, R. Boteva, A. Schramel, A.L. Horwich, F.-U. Hartl, "Chaperonin-mediated protein folding at the surface of groEL through a `molten globule'-like intermediate," Nature, 352:36-42, 1991. F.-Ulrich Hartl (Memorial Sloan Kettering Cancer Center, New York): "Molecular chaperones, proteins that help other proteins to fold, have emerged over recent years as an important topic of research in biology. While their physiological significance has been established through a combination
Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.

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