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tag physiology immunology neuroscience structural biology bacteria

Old brown dog with gray on its face and neck
Aging Dogs Provide Insights for Human Longevity
Hannah Thomasy, PhD, Drug Discovery News | Jul 19, 2023 | 6 min read
Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.
Immunology
The Scientist Staff | Nov 22, 1998 | 4 min read
K.C. Garcia, M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, I.A. Wilson, "An alpha-ß T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex," Science, 274:209-19, 1996. (Cited in more than 240 papers since publication) Comments by Ian A. Wilson, professor of molecular biology at The Scripps Research Institute in La Jolla, Calif. D.N. Garboczi, P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, D.C. Wiley, "Structure of the complex bet
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Dan Robitzski | Jan 25, 2023 | 6 min read
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
3D multicolored conceptual image representing hallucinogens and the human brain.
Natural High: Endogenous Psychedelics in the Gut and Brain
Iris Kulbatski, PhD | Sep 8, 2023 | 8 min read
Psychedelics are evolutionarily ancient compounds produced by fungi, plants, and microbes. Humans also synthesize psychedelics. Researchers want to know how and why.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?

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