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image: New Immunity

New Immunity

By | June 1, 2015

A scaffolding protein forms the hub of a newly identified immune pathway in plants.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.

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image: Nibbled? No Problem

Nibbled? No Problem

By | February 1, 2015

Making extra copies of their genomes allows some plants to better withstand damage.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Mitochondria Munchers

Mitochondria Munchers

By | November 1, 2014

Glial cells consume mitochondria released by neurons in the optic nerve.

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image: Cone Cell Correctors

Cone Cell Correctors

By | October 1, 2014

In mice, adult cone cell outer segments and their visual functions deteriorate if two microRNAs are not present.

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