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Synthetic Genomics
Synthetic Genomics

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image: Fungal Security Force

Fungal Security Force

By | February 1, 2016

In yew trees, Taxol-producing fungi function as an immune system to ward off pathogens.

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image: Managing Methylation

Managing Methylation

By | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Telomerase Overdrive

Telomerase Overdrive

By | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Adding Padding

Adding Padding

By | November 1, 2015

Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.

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image: Rethinking Lymphatic Development

Rethinking Lymphatic Development

By | August 1, 2015

Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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    The Nutshell Brazil’s Pre-Zika Microcephaly Cases

    A review of four years’ worth of medical records finds far greater numbers of microcephaly cases from before the ongoing Zika virus epidemic than had been officially reported.

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    Features The Mycobiome

    The largely overlooked resident fungal community plays a critical role in human health and disease.

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