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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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Pauses may help cells fine-tune gene expression.

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image: Researchers Identify Clue to Asymmetric Cell Division

Researchers Identify Clue to Asymmetric Cell Division

By | September 1, 2017

Phosphorylation of a surface protein on endosomes is key to the organelles’ uneven distribution in daughter cells.

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Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

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The presence of similar light-emitting enzymes in the distantly related organisms lends new insight into bioluminescence evolution.

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Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.  

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image: Rare T Cells Fight Cancer

Rare T Cells Fight Cancer

By | May 1, 2017

A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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While studying the progression of healthy cells into cancerous ones, researchers discover a way to engraft human blood cells into animals.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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