The Literature

Most Recent

image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

0 Comments

image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

0 Comments

image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

0 Comments

image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.

3 Comments

image: Rethinking Telomeres

Rethinking Telomeres

By | March 1, 2015

Not only do telomeres protect the ends of chromosomes, they also modulate gene expression over cells’ lifetimes.

2 Comments

image: B Cell Bosses

B Cell Bosses

By | February 1, 2015

Gut bacteria in mice spur regulatory B cells to differentiate and release an anti-inflammatory cytokine.

0 Comments

image: Bouncing Back

Bouncing Back

By | February 1, 2015

In mice, a transcriptional regulator, β-catenin, activates a microRNA-processing pathway in the nucleus accumbens to promote resilience to social stress.

0 Comments

image: Nibbled? No Problem

Nibbled? No Problem

By | February 1, 2015

Making extra copies of their genomes allows some plants to better withstand damage.

0 Comments

image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

7 Comments

image: Straighten Out

Straighten Out

By | January 1, 2015

Forces from bidirectional growth plates mechanically realign broken bones in infant mice.

0 Comments

Popular Now

  1. Major German Universities Cancel Elsevier Contracts
  2. Grass Routes
    Features Grass Routes

    Researchers are discovering a suite of new locations and functions of endocannabinoid receptors that play roles in sickness and in health.

  3. Running on Empty
    Features Running on Empty

    Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.

  4. Most of Human Genome Nonfunctional: Study
AAAS