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tag neuroscience structural biology cell molecular biology

Molecular/Structural Biology
The Scientist Staff | Jan 22, 1995 | 2 min read
J.H. Brown, T.S. Jardetzky, J.C. Gorga, L.J. Stern, R.G. Urban, J.L. Strominger, D.C. Wiley, "Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1," Nature, 364:33-9, 1993. (Cited in 235 publications through December 1994) Comments by Jerry H. Brown This paper is the first description of the three-dimensional structure of a class II human leukocyte antigen (HLA). Also known as histocompatibility antigens, the HLA molecules are present on various cell surfaces t
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Illustration of scientists collaborating
When Scientists Collaborate, Science Progresses
Meenakshi Prabhune, PhD | Dec 4, 2023 | 3 min read
Behind every successful scientist, there is another scientist.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Molecular Biology
The Scientist Staff | Mar 20, 1994 | 2 min read
Peter H. Seeburg (Center for Molecular Biology, University of Heidelberg): "In our brain, nerve cells communicate by chemical transmission at specialized structures termed synapses. Most excitatory synapses use the neurotransmitter L-glutamate, which activates specific receptor channels in the postsynaptic membrane. Molecularly and functionally different glutamate-activated channels are expressed by the brain, presumably tailored t
Molecular Biology
The Scientist Staff | Mar 20, 1994 | 2 min read
Peter H. Seeburg (Center for Molecular Biology, University of Heidelberg): "In our brain, nerve cells communicate by chemical transmission at specialized structures termed synapses. Most excitatory synapses use the neurotransmitter L-glutamate, which activates specific receptor channels in the postsynaptic membrane. Molecularly and functionally different glutamate-activated channels are expressed by the brain, presumably tailored t
Molecular Biology
The Scientist Staff | Oct 13, 1991 | 2 min read
Hot Papers Molecular Biology M.V. Milburn, L. Tong, A.M. deVos, A. Brünger, et al., "Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins," Science, 247:939-45, 1990. Sung-Hou Kim (University of California and Lawrence Berkeley Laboratory, Berkeley): "This paper provides three-dimensional structural information essential for (1) understanding the molecular switching mechanism for signal transduction i
Molecular Biology
The Scientist Staff | Jan 6, 1991 | 1 min read
B. Berkhout, R.H. Silverman, K.-T. Jeang, "Tat trans-activates the human immunodeficiency virus through a nascent RNA target," Cell, 59, 273-82, 20 October 1989. Ben Berkhout (National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md.): "The unique feature of this study was the use of RNA-refolding mutagenesis. Rearrangement of RNA structures was first described by Charles Yanofsky [Stanford University] to explain the process of transcriptional attenuation ["Transcription atten
Molecular Biology
The Scientist Staff | Oct 27, 1991 | 2 min read
S.J. Rhodes, S.F. Konieczny, "Identification of MRF4: a new member of the muscle regulatory factor gene family," Genes & Development, 3:2050-61, 1989. Stephen F. Konieczny (Purdue University, West Lafayette, Ind.): "This paper describes the identification and characterization of MRF4, the fourth member of a structurally and functionally related family of muscle regulatory factors that includes MyoD, myogenin, and Myf-5. Forced expression of MRF4 in fibroblasts converts nonmuscle cells to skele
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can

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