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The Literature

» immunology and cancer

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: B Cell Bosses

B Cell Bosses

By | February 1, 2015

Gut bacteria in mice spur regulatory B cells to differentiate and release an anti-inflammatory cytokine.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Long-Distance Call

Long-Distance Call

By | May 1, 2014

Neurons may use interferon signals transmitted over great distances to fend off viral infection.

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image: Going Long

Going Long

By | April 1, 2014

Researchers discover a tool to trigger an uncommon strategy cancer cells can use to lengthen their telomeres.

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image: Stem Cell Alter Egos

Stem Cell Alter Egos

By | April 1, 2014

Researchers show that cancer stem cells can exist in two distinct and interconvertible states.

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image: Exosome Tentacles

Exosome Tentacles

By | March 1, 2014

Unlike the usual smooth, spherical shape of exosomes, glioblastoma-derived exosomes appear to have long nanofilaments protruding from their surfaces.

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image: Viruses on the Brain

Viruses on the Brain

By | May 1, 2013

Viral infections of the central nervous system may trigger cytokines that induce seizures.

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image: Waking Cancer Cells

Waking Cancer Cells

By | December 1, 2012

A protein called Coco rouses dormant breast cancer cells in the lung.

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image: Drug Allergy in the Pocket

Drug Allergy in the Pocket

By | October 1, 2012

An HIV drug can bind to and alter the function of an immune molecule, causing a dangerous reaction in patients with a particular allele.

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