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image: Soluble Signal

Soluble Signal

By | May 1, 2015

An immune protein previously thought to mark inactive T cells has a free-floating form that correlates with HIV disease progression.


image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.


image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.


image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.


image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.


image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.


image: B Cell Bosses

B Cell Bosses

By | February 1, 2015

Gut bacteria in mice spur regulatory B cells to differentiate and release an anti-inflammatory cytokine.


image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.


image: Straighten Out

Straighten Out

By | January 1, 2015

Forces from bidirectional growth plates mechanically realign broken bones in infant mice.


image: Mitochondria Munchers

Mitochondria Munchers

By | November 1, 2014

Glial cells consume mitochondria released by neurons in the optic nerve.

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