The Literature

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

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image: Straighten Out

Straighten Out

By | January 1, 2015

Forces from bidirectional growth plates mechanically realign broken bones in infant mice.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Going Long

Going Long

By | April 1, 2014

Researchers discover a tool to trigger an uncommon strategy cancer cells can use to lengthen their telomeres.

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image: Stem Cell Alter Egos

Stem Cell Alter Egos

By | April 1, 2014

Researchers show that cancer stem cells can exist in two distinct and interconvertible states.

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image: Exosome Tentacles

Exosome Tentacles

By | March 1, 2014

Unlike the usual smooth, spherical shape of exosomes, glioblastoma-derived exosomes appear to have long nanofilaments protruding from their surfaces.

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image: Avoiding Salt

Avoiding Salt

By | January 1, 2014

In a newly identified tropism, plant roots steer clear of salinity.

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image: Flexible Cells

Flexible Cells

By | September 1, 2013

When stretched, lung cells signal to each other by releasing ATP.

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