The Literature

» cancer, disease/medicine and structural biology

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image: Managing Methylation

Managing Methylation

By | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Telomerase Overdrive

Telomerase Overdrive

By | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Going Long

Going Long

By | April 1, 2014

Researchers discover a tool to trigger an uncommon strategy cancer cells can use to lengthen their telomeres.

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image: Stem Cell Alter Egos

Stem Cell Alter Egos

By | April 1, 2014

Researchers show that cancer stem cells can exist in two distinct and interconvertible states.

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image: Exosome Tentacles

Exosome Tentacles

By | March 1, 2014

Unlike the usual smooth, spherical shape of exosomes, glioblastoma-derived exosomes appear to have long nanofilaments protruding from their surfaces.

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image: Intracellular Spirals

Intracellular Spirals

By | December 1, 2013

Membrane twists connect stacked endoplasmic reticulum sheets.

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