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» cell & molecular biology and neuroscience

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image: The Regenerators

The Regenerators

By | September 1, 2015

A molecular signature makes it possible to trace the details of hair cell replacement in the mammalian inner ear.

1 Comment

image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.

3 Comments

image: Bouncing Back

Bouncing Back

By | February 1, 2015

In mice, a transcriptional regulator, β-catenin, activates a microRNA-processing pathway in the nucleus accumbens to promote resilience to social stress.

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image: Tangle Trigger

Tangle Trigger

By | January 1, 2015

An enzyme that cleaves tau protein in acidic cellular conditions may trigger early events in Alzheimer’s disease.

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image: Mitochondria Munchers

Mitochondria Munchers

By | November 1, 2014

Glial cells consume mitochondria released by neurons in the optic nerve.

1 Comment

image: Mixed Signals

Mixed Signals

By | November 1, 2014

Individual neurons in the dorsomedial striatum integrate responses to sight and touch.

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image: Rhythmic Rewiring

Rhythmic Rewiring

By | November 1, 2014

Circadian neurons in fruit flies form synapses with different, noncircadian brain regions depending on the time of day.

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